Combination of oral all trans retinoic acid and chemotherapy can acute promyelocytic leukemia in complete molecular biology alleviates. But oral ATRA alone can not achieve these results. The exclusive use of liposomes coated all trans retinoic acid can be effective in newly diagnosed APL patients achieving complete molecular biology alleviate The researchers believe that the lipoATRA and oral ATRA have higher serum concentration and duration.
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